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Anchor 1

Cancer:

  • Development of PKI targeting Npm-ALK and the study of conformational  plasticity and binding kinetics.

  • How kinases define specificity in lipid signaling. (Ambizione).

  • Inhibitory therapeutics for treatment of autoimmune disorders.

Anchor 2

Neglected/Orphan disease:

  • Pre-clinical evaluation of Rimeporide, NHE1 inhibitor and drug repurposing in Duchenne muscular dystrophy.​

  • Targeting RNA stem-loop structure regulating the alternative splicing of SMN2: a new therapeutic target in Spinal Muscular Atrophy.

  • Identifying and developing new therapeutic concepts for the treatment of neglected diseases.

 

  • Scaffolds for Alternative Delivery (SADEL) for IBD.

Antibiotics:

  • Identification and characterization of novel antibacterial compounds using protozoan hosts.

Anchor 3
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