Design and development of standard and innovative biological tools that contributed to the identification and characterization of allosteric modulators of GPCR and non-GPCR targets in inflammation and cancer immunotherapy.
Expertise fields: Cell-based assays development, molecular biology, pharmacology for receptors, cell line generation, orthosteric and allosteric compounds, small molecules.
Phone: +41 (0)22 379 33 76
Lab manager responsible of:
General Lab management (orders and contact with suppliers, setting up security protocols).
C lab (radioprotection expert) and P2 cell lab.
Transmission of basic laboratory techniques and protocols to new employees and students.
Chemicals, biological reagents and cell databases.
Training Biology technician apprentices (apprenti laborant en biologie).
Main technical expertise: Cell culture, Molecular biology (Tissue and cell RNA or DNA extraction, mouse genotyping, PCR and qPCR, cloning), Mouse muscle fiber preparation, AAVirus production, Recombinant protein expression in E. coli or SF9 cells, Protein purification, DNA, RNA and protein electrophoresis, Western blot, Microscale Thermophoresis, Enzymatic assay, immunocyto-histology.
Phone: +41 (0)22 379 33 73
Technical expertise in molecular biology (DNA extraction, PCR, DNA electrophoresis and cloning), histology techniques (Cryostat and paraffin cutting, histology staining, immunofluorescence and histological analysis), mouse handling, muscle fiber preparation and some laboratory tasks.
Phone: +41 (0)22 379 33 77